apparent diffusion coefficient adc maps (Bruker Corporation)
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Bruker Corporation
apparent diffusion coefficient adc maps
Apparent Diffusion Coefficient Adc Maps, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 97/100, based on 3085 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/apparent+diffusion+coefficient+adc+maps/Diffusion/bio_rxiv__2025__10__22__684053-75-0-10
Average 97 stars, based on 3085 article reviews
Apparent Diffusion Coefficient Adc Maps, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 97/100, based on 3085 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/apparent+diffusion+coefficient+adc+maps/Diffusion/bio_rxiv__2025__10__22__684053-75-0-10
Average 97 stars, based on 3085 article reviews
apparent diffusion coefficient adc maps - by Bioz Stars,
2026-10
97/100 stars
Images
1) Product Images from "Multimodal Characterization and Evolution of Malonate-induced Stroke Model: Advanced MRI, Histology-Molecular Profiling"
Article Title: Multimodal Characterization and Evolution of Malonate-induced Stroke Model: Advanced MRI, Histology-Molecular Profiling
Journal: bioRxiv
doi: 10.1101/2025.10.22.684053
Figure Legend Snippet: A. The percentage of viable and necrotic tissue with respect to the total lesion volume. B.The evolution of vessel radius (R). C. Blood volume fraction (BVF). D. Oxygen saturation (StO 2 ) E. Signal enhancement F. Apparent diffusion coefficient (ADC) observed by MRI at D4, D7, D14, D28, and D56 after ischemic injury by malonate injection. n=5 at D4, n=13 at D7, n=8 at D14, n=8 at D28 and n=7 at D56. Data is represented by medians and IQR. *: 0.03>p>0.01, **: 0.005>p>0.001, ***: 0.0005>p>0.0001, ****: p<0.0001 vs contralateral hemisphere, paired non-parametric Mann-Whitney test.
Techniques Used: Diffusion-based Assay, Injection, MANN-WHITNEY
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![FIGURE 2 (A) Representative images obtained in one rat at 3 h following the MCAo. The <t>ADC</t> map depicts the core of ischemia (arrow). The time-to-peak map reveals a larger zone of hypoperfusion (arrow). The penumbra was delineated as the mismatch between perfusion and diffusion abnormalities (hatched purple). The StO2-MRI map shows the area with reduced oxygen saturation (arrow). [18F]-FMISO-PET delineates the hypoxic area with increased retention of [18F]-FMISO (arrow). The T2-W image, acquired 24 h after the MCAo, shows the consolidated lesion (arrow). (B) Evolution of ADC-defined lesion volumes. The lesion demonstrable at 15 min expanded at 3 h, and even more so at 24 h following the MCAo. **p < 0.01; ***p < 0.001; ANOVA with repeated measures followed by Tukey's post hoc test. The boxes define the interquartile range; the solid horizontal line the median, and the whiskers represent the minimal and maximal values. (C) Volumes of brain compartments at 3 h following the MCAo. Time-to-peak (TTP): tissue volume with decreased perfusion; Penumbra: tissue with PWI/DWI mismatch; StO2-MRI: tissue that displays a decrease in oxygen saturation; [18F]-FMISO-PET: tissue volume that shows an increased retention of [18F]-FMISO. The boxes define the interquartile range; the solid horizontal line the median and the whiskers represent the minimal and maximal values. ADC, apparent diffusion <t>coefficient;</t> ANOVA, analysis of variance; DWI, diffusion-weighted imaging; MCAo, middle cerebral artery occlusion; PET, positron emission tomography; PWI, perfusion-weighted imaging; StO2-MRI, magnetic resonance-based imaging of brain oxygen saturation; T2-W, T2-weighted; [18F]-FMISO, 18-fluorine-fluoromisonidazole](https://pub-med-unpaywalled-images-cdn.bioz.com/pub_med_ids_ending_with_5719/pm36285719/pm36285719__page5_image1.jpg)
![FIGURE 5 Representative images of StO2-MRI, [18F]-FMISO-PET, and the superimposition of both abnormalities on the ADC image for each animal. StO2-MRI abnormality is delinated in yellow and [18F]-FMISO-PET abnormality in green. ADC, apparent diffusion coefficient; [18F]-FMISO, 18-fluorine-fluoromisonidazole; PET, positron emission tomography; StO2-MRI, magnetic resonance-based imaging of brain oxygen saturation; SUV, standardized uptake value](https://pub-med-unpaywalled-images-cdn.bioz.com/pub_med_ids_ending_with_5719/pm36285719/pm36285719__page8_image1.jpg)